The molecule of a specific structure is selected, and a self-assembled monomolecular membrane technique is used to utilize a specific chemical bond on the surface of the optical glass, so that the molecules of a specific structure are connected to the glass by chemical bonding according to a certain regular arrangement of head and tail. A layer of water-repellent, anti-bacterial, anti-mild, solvent-resistant, anti-friction, corrosion-resistant, wash-resistant single-molecule anti-fungal coating.